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If you are using a limited card pool I would just use what you have the most of. Most offenses focus on abusing a couple combos such as Jacob + RTC, ET + AoCP, or Hidden Treasures + ANB + FBTN characters. Genesis offenses that utilize Jacob, Zeb, Benjamin and CotH usually are pretty effective. I also like using Joshua the HP/Phinehas with Zeal. T2 offenses usually try to take advantage of pre-block ignore, FBTN or CBN battle winners such as AoCP, zeal, etc. Gold offenses can also be very good with all the converts and SWJs. For defense you usually need a mix of low and high numbered guys so you don't get caught off guard. I have found a crimson defense with Leviathan, Nebby, Nebushaban, etc to be very good. I usually run 4 or 5 Mid Attacks, 3 or 4 Nebby's Prides and a couple bel's banquets. Some other popular defenses are Phillys, demons, and stand alones.
It still needs another good card