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at what point are you allowed to switch out the generic LS's in booster? Since we have abilities that depend on NT and OT souls it could make a difference which ones you use. Also, there is no reserve in booster correct?
Each player is responsible for bringing 8 regular lost soul cards (no special abilities) to the table. You will need 7 lost soul cards if you play a 50 to 56 card deck. You will need 8 lost soul cards if you play a 56 to 63 card deck. If you pull a lost soul card from a pack then you can substitute it for one that you brought to the table. This is the only way you will be able to play a lost soul card that has a special ability.
Closed deck categories do not use the Reserve.
Minor comment. I like that you said a Moabite defense pairs with OT LS. Is there a resource where you could look up a theme (Romans, Moabites, etc...) that also shows what pairs well with them?