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If TGT was in play and your opponent had a Redeemed Soul (so TGT worked) and there were few enough Crimson ECs in play, I think you could set aside the Crimson ECs except Zimri to activate the ignore on TGT, stopping his ability that way.
If you Discard a Negate with Zimri's ability, they play He Is Risen, can you then use that Negate to Negate He Is Risen?